- Monitor Regular thyroid function tests (TSH, T4)
- Monitor heart rate, blood pressure, and clinical signs of over- or under-replacement
- Adjust dose based on weight changes and lab results
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Thyrox 12.5 is a synthetic thyroid hormone replacement used in the treatment of hypothyroidism, a condition where the thyroid gland fails to produce adequate thyroid hormone. Restoring normal hormone levels helps regulate energy, metabolism, and overall body function.
Thyrox 12.5 contains levothyroxine sodium, a synthetic form of the natural thyroid hormone T4. It increases basal metabolic rate (BMR), promotes protein synthesis, and stimulates metabolism of carbohydrates, fats, and vitamins. Its activity is largely mediated through conversion to triiodothyronine (T3) at the cellular level, influencing growth, development, and metabolic regulation.
Your healthcare provider will determine the appropriate starting dose based on your thyroid hormone levels, assessed via blood tests. Once therapy begins, periodic monitoring is essential to ensure optimal dose adjustment and therapeutic effectiveness.
Mild Hypothyroidism: 1.7 mcg/kg/day; usual initial dose: 25–50 mcg/day.
Age >50 or with cardiovascular disease: Start at 12.5–25 mcg/day; titrate every 4–8 weeks.
Severe Hypothyroidism: Begin with 12.5–25 mcg/day; increase by 25 mcg/day every 2–4 weeks as needed.
Neonates & Infants (1–12 months): 6–15 mcg/kg/day.
Children (1–12 years): 4–6 mcg/kg/day.
Adolescents (>12 years): 2–3 mcg/kg/day or up to 150 mcg/day.
Side effects often result from excessive dosing and may include:
Keep in a dry place away from light and heat. Keep out of the reach of children.
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.